List Books » Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding
Authors: Alan Fersht
ISBN-13: 9780716732686, ISBN-10: 0716732688
Format: Hardcover
Publisher: Freeman, W. H. & Company
Date Published: September 1998
Edition: 1st Edition
For this text, Fersht offers four new chapters showing the impact of protein engineering on protein folding and catalysis (one on enzymology; three on specifics aspects of protein folding).
Extensively rewritten chapters cover:
1. The Three-dimensional Structure of Proteins
2. Chemical Catalysis
3. The Basic Equations of Enzyme Kinetics
4. Measurement and Magnitude of Enzymatic Rate Constants
5. The pH Dependence of Enzyme Catalysis
6. Practical Kinetics
7. Detection of Intermediates in Reactions by Kinetics
8. Stereochemistry of Enzymatic Reactions
9. Active-site-directed and Enzyme-activated Irreversible Inhibitors: Affinity Labels and Suicide Inhibitors
10. Conformational Change, Allosteric Regulation, Motors, and Work
11. Forces Between Molecules and Enzyme-Substrate Binding Energies
12. Enzyme-substrate Complementarity and the Use of Binding Energies in Catalysis
13. Specificity and Editing Mechanisms
14. Recombinant DNA Technology
15. Case Studies of Enzyme Structure and Mechanism
16. Protein Engineering
17. Protein Stability
18. Kinetics of Protein Folding
19. Folding Pathways and Energy Landscapes