Fetology: Diagnosis and Management of the Fetal Patient, Second Edition » (2nd Edition)

Diana W. Bianchi, MD
Natalie V. Zucker Professor of Pediatrics, Obstetrics,

and Gynecology

Tufts University School of Medicine

Vice Chair for Research and Academic Affairs

Department of Pediatrics

Floating Hospital for Children at Tufts Medical Center

Boston, MA

Timothy M. Crombleholme, MD
Richard G and Geralyn Azizkhan Chair in Pediatric

Surgery

Professor of Surgery, Pediatrics (Molecular and

Developmental Biology), and Obstetrics and

Gynecology

Director, Fetal Care Center of Cincinnati

University of Cincinnati College of Medicine

Associate Director of the Cincinnati Children’s

Research Foundation

Cincinnati Children’s Hospital Medical Center

Cincinnati, OH

Mary E. D'Alton, MD

Willard c. Rappelye Professor of Obstetrics and Gynecology

Chair, Department of Obstetrics and Gynecology

Director, Obstetrics and Gynecology Services

Columbia University Medical Center

Sloane Hospital for Women

New York Presbyterian Hospital

Columbia University, College of Physicians and Surgeons

New York, NY

Fergal D. Malone, MD

Professor and Chairman

Department of Obstetrics and Gynecology

Vice Dean

School of Medicine

Royal College of Surgeons in Ireland

The Rotunda Hospital

Dublin, Ireland

The first book to synthesize relevant, critically reviewed data for application to the diagnosis and treatment of prenatal patients— updated and in full color

5 STAR DOODY'S REVIEW!

"The book is comprehensive, concise, well illustrated, and an extremely valuable resource for perinatal healthcare providers....This book has rapidly become a go-to reference in the perinatal field and this new edition confirms its place as the gold standard in the field. Perinatologists will find this to be an essential part of their library. As more obstetric practitioners do investigative sonographic procedures in their offices, this book will be a valuable resource for them as well. The new edition is overdue and most welcome."—Doody's Review Service

Fetology: Diagnosis and Management of the Fetal Patient offers a cross-disciplinary approach that goes beyond the traditional boundaries of obstetrics, pediatrics, and surgery to help you effectively diagnose and treat fetal patients. Fetology considers the full implications of a fetal sonographic or chromosomal diagnosis—from prenatal management to long-term outcome—for an affected child. Here, you’ll find all the insights you need to answer the questions of parents faced with a diagnosis of a fetal abnormality—and present them with a coordinated therapeutic plan.

Features

• NEW! Full-color design
• NEW! Five new chapters on Adrenal Masses, Abdominal Cysts, Overgrowth, Mosaic Trisomy, and DiGeorge Syndrome
• NEW! Chapters summarizing contemporary approaches to first and second trimester screening for aneuploidy
• NEW! 3D ultrasound and MRI images: over 450 images clearly illustrate the diagnosis of anomalies with the latest, most precise imaging technology
• NEW! Key Points open each chapter, providing rapid review of a particular condition
• Highlighted treatment/management guidelines deliver quick access to practical, what-to-do information
• Each chapter, which covers a single anomaly, includes description of the medical condition, incidence, characteristic sonographic findings, differential diagnosis, best treatment during pregnancy, treatment of the newborn, expected outcome, and more
• Addresses gaps in our knowledge that highlight unmet clinical needs and areas for future research

Prefaces Acknowledgments
Part I: Introduction
Chapter 1: Prenatal Imaging Chapter 2: First Trimester Screening for Aneuploidy Chapter 3: Second Trimester Screening for Aneuploidy Chapter 4: Prenatal Diagnostic Procedures Chapter 5: Fetal Intervention
Part II: Management of Fetal Conditions Diagnosed by Sonography
Section A: Central Nervous System Chapter 6: Agenesis of the Corpus Callosum Chapter 7: Anencephaly Chapter 8: Arachnoid Cyst Chapter 9: Cerebral Calcifications Chapter 10: Craniosynostosis Chapter 11: Dandy-Walker Malformation and Variants Chapter 12: Encephalocele Chapter 13: Exencephaly/Acrania Chapter 14: Holoprosencephaly Chapter 15: Hydranencephaly Chapter 16: Hydrocephalus Chapter 17: Intracranial Hemorrhage Chapter 18: Macrocephaly Chapter 19: Myelomeningocele Chapter 20: Microcephaly Chapter 21: Porencephaly Chapter 22: Vein of Galen Aneurysm Section B: Craniofacial Chapter 23: Cleft Lip and Cleft Palate Chapter 24: Hemifacial Microsomia Chapter 25: Hypertelorism Chapter 26: Hypotelorism Chapter 27: Macroglossia Chapter 28: Micrognathia and Agnathia Chapter 29: Microphthalmia/Anophthalmia Section C: Neck Chapter 30: Congenital High Airway Obstruction Syndrome Chapter 31: Cystic Hygroma in Early Pregnancy Chapter 32: Cystic Hygroma in Late Pregnancy Chapter 33: Goiter Section D: Thoracic Chapter 34: Bronchopulmonary Sequestration Chapter 35: Cystic Adenomatoid Malformation Chapter 36: Other Cystic Lesions of the Chest Chapter 37: Congenital Diaphragmatic Hernia Chapter 38: Hydrothorax Chapter 39: Pulmonary Agenesis Chapter 40: Esophageal Atresia and Tracheoesophageal Fistula Section E: Cardiovascular Chapter 41: Tachyarrhythmias Chapter 42: Bradyarrhythmias Chapter 43: Atrial Septal Defects Chapter 44: Ventricular Septal Defects Chapter 45: Atrioventricular Canal Defect Chapter 46: Ebstein Anomaly Chapter 47: Hypoplastic Right Ventricle Chapter 48: Hypoplastic Left Ventricle Chapter 49: Pulmonary Stenosis and Atresia Chapter 50: Aortic Stenosis Chapter 51: Coarctation of the Aorta Chapter 52: Tetraology of Fallot Chapter 53: Double Outlet Right Ventricle Chapter 54: Truncus Arteriosus Chapter 55: Transposition of Great Arteries Chapter 56: Heterotaxy Syndrome Chapter 57: Cardiomyopathy Chapter 58: Intracardiac Tumors Section F: Abdominal-Wall Defects Chapter 59: Ectopia Cordis Chapter 60: Body-Stalk Anomaly Chapter 61: Pentalogy of Cantrell Chapter 62: Omphalocele Chapter 63: Gastroschisis Chapter 64: Cloacal Exstrophy Chapter 65: Bladder Exstrophy Section G: Gastrointestinal Tract Chapter 66: Cystic Lesions of the Abdomen Chapter 67: Choledochal Cyst Chapter 68: Ovarian Cysts Chapter 69: Intra-abdominal Calcifications—Hepatic Chapter 70: Intra-abdominal Calcifications Chapter 71: Pyloric Atresia and Stenosis Chapter 72: Duodenal Atresia and Senosis Chapter 73: Jejunoileal Atresia and Stenosis Chapter 74: Colonic Atresia Chapter 75: Hirschsprung's Disease Chapter 76: Imperforate Anus Section H. Genitourinary Tract Chapter 77: Echogenic Kidneys Chapter 78: Multicystic Dysplastic Kidney Chapter 79: Polycystic Kidney Disease Chapter 80: Hydronephrosis: Minimal Chapter 81: Hydronephrosis: Ureteropelvic Junction Obstruction Chapter 82: Hydronephrosis: Bladder Outlet Obstruction Chapter 83: Hydronephrosis: Ectopic Ureterocele Chapter 84: Ambiguous Genitalia Chapter 85: Persistent Cloaca Chapter 86: Renal Agenesis Chapter 87: Sirenomelia Section I: Skeletal Chapter 88: Hemivertebrae Chapter 89: Achondroplasia Chapter 90: Thanatophoric Dysplasia Chapter 91: Osteogenesis Imperfecta Chapter 92: Campomelic Dysplasia Chapter 93: Diastrophic Dysplasia Chapter 94: Ellis-van Creveld Syndrome Chapter 95: Short Rib Polydactyly Syndrome Chapter 96: Jarcho-Levin Syndrome Chapter 97: Achondrogenesis Chapter 98: Hypophosphatasia Chapter 99: Chondrodysplasia Punctata Section J: Extremities Chapter 100: Amniotic Band Syndrome Chapter 101: Arthrogryposis Chapter 102: Clinodactyly Chapter 103: Ectrodactyly Chapter 104: Polydactyly Chapter 105: Syndactyly Chapter 106: Radial Aplasia Chapter 107: Clubfoot Section K: Umbilical Cord Chapter 108: Umbilical Cord Abnormalities Chapter 109: Single Umbilical Artery Section L: Tumors Chapter 110: Cervical Teratoma Chapter 111: Liver Tumors Chapter 112: Mesoblastic Nephroma Chapter 113: Neuroblastoma Chapter 114: Retinoblastoma Chapter 115: Sacrococcygeal Teratoma Chapter 116: Wilms' Tumor Section M: Multiple Gestation Chapter 117: Malformations in Twins Chapter 118: Intrauterine Death in One Twin Chapter 119: Twin-to-Twin Transfusion Syndrome Chapter 120: Twin Reversed Arterial Perfusion Sequence Chapter 121: Conjoined Twins Chapter 122: Monoamniotic Twins Section N: Disorders of Growth Chapter 123: Intrauterine Growth Restriction Chapter 124: Overgrowth Syndromes Section O: Disorders of Amniotic Fluid Volume Chapter 125: Oligohydramnios Chapter 126: Polyhydramnios Section P: Hydrops Fetalis Chapter 127: Immune Hydrops Chapter 128: Nonimmune Hydrops Fetalis
Part III: Management of Fetal Chromosome Abnormalities
Chapter 129: Trisomy 13
Chapter 130: Trisomy 18
Chapter 131: Trisomy 21 (Down Syndrome)
Chapter 132: Triploidy Chapter 133: Other Autosomnal Aneuploidies Chapter 134: 45, X (Turner Syndrome)
Chapter 135: 47,XXY (Klinefelter Syndrome)
Chapter 136: 47,XXX Karyotype (Triple X Syndrome, Trisomy X)
Chapter 137: 47,XYY Chapter 138: Tetrasomy 12p (Pallister-Killian Syndrome)
Chapter 139: 22q11.2 Deletion (DiGeorge Syndrome)
Index

Diana W. Bianchi, MD
Natalie V. Zucker Professor of Pediatrics, Obstetrics,

and Gynecology

Tufts University School of Medicine

Vice Chair for Research and Academic Affairs

Department of Pediatrics

Floating Hospital for Children at Tufts Medical Center

Boston, MA

Timothy M. Crombleholme, MD
Richard G and Geralyn Azizkhan Chair in Pediatric

Surgery

Professor of Surgery, Pediatrics (Molecular and

Developmental Biology), and Obstetrics and

Gynecology

Director, Fetal Care Center of Cincinnati

University of Cincinnati College of Medicine

Associate Director of the Cincinnati Children’s

Research Foundation

Cincinnati Children’s Hospital Medical Center

Cincinnati, OH

Mary E. D'Alton, MD

Willard c. Rappelye Professor of Obstetrics and Gynecology

Chair, Department of Obstetrics and Gynecology

Director, Obstetrics and Gynecology Services

Columbia University Medical Center

Sloane Hospital for Women

New York Presbyterian Hospital

Columbia University, College of Physicians and Surgeons

New York, NY

Fergal D. Malone, MD

Professor and Chairman

Department of Obstetrics and Gynecology

Vice Dean

School of Medicine

Royal College of Surgeons in Ireland

The Rotunda Hospital

Dublin, Ireland