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Vascular Cognitive Impairment: Preventable Dementia » (First Edition)

Book cover image of Vascular Cognitive Impairment: Preventable Dementia by John V. Bowler

Authors: John V. Bowler (Editor), Vladimir Hachinski
ISBN-13: 9780192632678, ISBN-10: 0192632671
Format: Hardcover
Publisher: Oxford University Press, USA
Date Published: June 2003
Edition: First Edition

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Author Biography: John V. Bowler

Royal Free and University College Medical School London

University of Western Ontario

Book Synopsis

In recent years there has been a radical reapprisal of the concept of vascular dementia. There has been a move away from an Alzheimer-based diagnostic paradigm towards one more appropriately tailored for vascular disease. Vascular Cognitive Impairment presents a new definition for this class of cerebrovascular, neurodegenerative process with an emphasis on early detection, prompt treatment and the prevention of disease progression.
Vascular Cognitive Impairment: A Preventable Senility presents an overview of the current state of our knowledge in this field. It reviews the historical background, prevalence, risk factors and economic consequences of the condition. In addition, the book summarises our knowledge of the pathological process, describing insight derived from genetic and imaging studies, before examining opportunities for early diagnosis, prevention and the options for management, both now, and as a result of ongoing clinical trials. With contributions from an expert team of international contributors, this book provides a comprehensive summary of the state-of-the-art in this field, providing a framework for a new understanding of a complex and debilitating condition.

Doody Review Services

Reviewer:Paula M Cotruta, M.D.(University of Illinois at Chicago College of Medicine)
Description:This book is an excellent review of one of the few preventable causes of dementia: vascular cognitive impairment. It is very well structured, addressing all aspects of this condition in detail, from diagnostic criteria to histopathology, genetics, anatomical imaging, and clinical trials and treatment.
Purpose:The purpose is to characterize vascular cognitive impairment as a possible preventable condition if detected early. Given the fact that cerebrovascular disease is an important factor contributing to cognitive impairment, this book is definitely needed. The author's objective is excellently fulfilled. The book covers in detail all aspects of vascular cognitive impairment.
Audience:It is written mainly for specialists, meaning general neurologists, primary care physicians interested in geriatrics, neuropsychologists, or researchers. The author is a credible authority in this subject. The list of contributors is impressive and include well known, international specialists.
Features:The book covers in detail all aspects of vascular cognitive impairment from history and current criteria to physiopathology, imaging, and treatment. I was particularly impressed with the review of current diagnostic criteria including limitations and inter-rater reliability. The chapter on anatomical imaging is extremely valuable for the clinical practitioner, as it draws correlations between the type and amount of radiological abnormalities and the impact on cognition. The book has numerous tables and the information is well organized and presented in a easy to read manner. Because it is so detailed, the book is suitable for specialists who want to expand their knowledge about this specific condition but it is less so for beginners (students, residents).
Assessment:This is an excellent review of vascular dementia. It is difficult to compare it with the classical neurology textbooks that addresses dementias in general.

Table of Contents

Preface
List of Contributors
1Current criteria for vascular dementia - a critical appraisal1
2Historical evolution of the concept of vascular dementia12
3Prevalence and incidence patterns of vascular dementia21
4Evidence-based prognosis of vascular dementia: survival and rate of cognitive decline33
5The cost of vascular cognitive impairment51
6Histopathology57
7Experimental models of vascular dementia: A focus on white matter disease and incomplete infarction76
8Genetics of vascular dementia93
9Behavioral and psychological symptoms in vascular cognitive impairment110
10Cognitive patterns126
11Measurement of cognition139
12Neuropsychological differentiation of Alzheimer's disease and vascular dementia153
13Anatomical imaging176
14Cerebral blood flow and metabolism in vascular dementia193
15Neurochemical markers208
16Subtypes of vascular dementia and their pathogenesis: a critical overview217
17White matter changes in vascular dementia230
18Post-stroke dementia239
19Vasculitis, collagen vascular disease, and vascular dementia251
20Vascular disorders and Alzheimer's disease260
21Treatment of vascular dementias277
22Clinical trials in vascular dementia293
23Prevention308
24Vascular cognitive impairment - a new concept321
Index339

Subjects