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Traditional Medicinal Plants and Malaria »

Book cover image of Traditional Medicinal Plants and Malaria by Merlin Willcox

Authors: Merlin Willcox (Editor), Gerard Bodeker (Editor), Philippe Rasoanaivo
ISBN-13: 9780415301121, ISBN-10: 0415301122
Format: Hardcover
Publisher: CRC Press
Date Published: June 2004
Edition: (Non-applicable)

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Author Biography: Merlin Willcox

Book Synopsis

Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The world’s poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimalarial drugs.

The first book to be published on this subject, Traditional Medicinal Plants and Malaria explores the evidence for the safety and efficacy of some of these traditional medicines, and presents practical guidelines for designing studies on traditional plant-based antimalarial medicines, mosquito repellents, and insecticides. Systematic reviews of the literature and consensus guidelines form the main body of the book. Ethnomedical, ethnobotanical, pharmacological, phytochemical, toxicological, and clinical aspects of herbal antimalarials are also reviewed. These are supplemented by case studies of the most well-known traditional antimalarials.

Table of Contents

Forewordxix
Introductionxxiii
Part 1Traditional Medicine and Malaria Control
Chapter 1Malaria Control in Africa and the Role of Traditional Medicine3
Part 2Case Studies of Plant-Based Medicines for Malaria
Chapter 2Cinchona21
Chapter 3Artemisia annua as a Traditional Herbal Antimalarial43
Chapter 4Changshan (Dichroa febrifuga)--Ancient Febrifuge and Modern Antimalarial: Lessons for Research from a Forgotten Tale61
Chapter 5Ayush-6483
Chapter 6Neem (Azadirachta indica)91
Chapter 7Malarial-5: Development of an Antimalarial Phytomedicine in Mali117
Chapter 8Cryptolepis sanguinolenta131
Chapter 9Strychnos myrtoides: A Case Study of a Chemosensitising Medicinal Plant141
Part 3Ethnomedical Research
Chapter 10Frequency of Use of Traditional Herbal Medicines for the Treatment and Prevention of Malaria: An Overview of the Literature161
Chapter 11An Overview of Ethnobotanical Studies on Plants Used for the Treatment of Malaria187
Chapter 12The Discovery of Indigenous Febrifuges in the British East Indies, c. 1700-1820199
Chapter 13The Ayurvedic Perspective on Malaria205
Chapter 14Guidelines for Ethnobotanical Studies on Traditional Antimalarials215
Part 4Laboratory Research
Chapter 15Pharmacological Properties of the Active Constituents of Some Traditional Herbal Antimalarials231
Chapter 16Guidelines for the Nonclinical Evaluation of the Efficacy of Traditional Antimalarials255
Chapter 17Models for Studying the Effects of Herbal Antimalarials at Different Stages of the Plasmodium Life Cycle271
Chapter 18Guidelines for the Preclinical Evaluation of the Safety of Traditional Herbal Antimalarials279
Part 5Clinical Research
Chapter 19An Overview of Clinical Studies on Traditional Herbal Antimalarials297
Chapter 20Observational Methods for Assessing Traditional Antimalarials311
Chapter 21Guidelines for Clinical Studies on Herbal Antimalarials321
Part 6Repellence and Vector Control
Chapter 22An Overview of Plants Used as Insect Repellents343
Chapter 23Guidelines for Studies on Plant-Based Insect Repellents365
Chapter 24An Overview of Plants Used for Malaria Vector Control375
Chapter 25Guidelines for Studies on Plant-Based Vector Control Agents389
Epilogue: Prospects for the Future409
Glossary of Technical Terms and Abbreviations415
Index417

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