Authors: Eric Lax
ISBN-13: 9780805077780, ISBN-10: 0805077782
Format: Paperback
Publisher: Holt, Henry & Company, Inc.
Date Published: February 2005
Edition: First Edition
Eric Lax is the author of Woody Allen, A Biography and Life and Death on 10 West, both New York Times Notable Books. His work has appeared in The New York Times Magazine, Vanity Fair, Life, The Atlantic Monthly, and Esquire, as well as in many other magazines and newspapers. He lives with his wife and two sons in Los Angeles.
"Admirable, superbly researched . . . perhaps the most exciting tale of science since the apple dropped on Newton's head."
—Simon Winchester, The New York Times
Alexander Fleming's discovery of penicillin in his London laboratory in 1928 and its eventual development as the first antibiotic by a team at Oxford University headed by Howard Florey and Ernst Chain in 1942 led to the introduction of the most important family of drugs of the twentieth century.
Yet credit for penicillin is largely misplaced. Neither Fleming nor Florey and his associates ever made real money from their achievements; instead it was the American labs that won patents on penicillin's manufacture and drew royalties from its sale. Why this happened, why it took fourteen years to develop penicillin, and how it was finally done is a fascinating story of quirky individuals, missed opportunities, medical prejudice, brilliant science, shoestring research, wartime pressures, misplaced modesty, conflicts between mentors and their protégés, and the passage of medicine from one era to the next.
By reminding us of the stellar contributions to that same story that were made by the Oxford University team of Howard Florey, Ernest Chain and a hitherto utterly anonymous chemist named Norman Heatley, Mr. Lax has performed a service to science of which he should be proud and all must be grateful.
Introduction: The Reclaimed Life | 1 | |
1. | The Quiet Scot | 7 |
2. | The Rough Colonial Genius | 32 |
3. | The Money Talks | 51 |
4. | The Temperamental Continental | 59 |
5. | The Micro Master | 69 |
6. | "Without Heatley, No Penicillin" | 85 |
7. | Eight Mice | 114 |
8. | Blitzed | 136 |
9. | "Will These Plans Come to Grief?" | 157 |
10. | The Friend in Deed | 171 |
11. | The Kilo That Never Came | 197 |
12. | The Laurel Wreath of Credit | 210 |
13. | The Thinking in Stockholm | 230 |
14. | The Makers of Great Medicine | 249 |
Notes | 265 | |
Bibliography | 289 | |
Acknowledgments | 292 | |
Index | 295 |