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Pharmacology for Nursing Care » (7th Edition)

Book cover image of Pharmacology for Nursing Care by Richard A. Lehne

Authors: Richard A. Lehne
ISBN-13: 9781416062493, ISBN-10: 1416062491
Format: Hardcover
Publisher: Elsevier Health Sciences
Date Published: July 2009
Edition: 7th Edition

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Author Biography: Richard A. Lehne

Formerly Lecturer, University of Arizona College of Nursing, Lecturer, University of Virginia School of Nursing, Research Assistant Professor, Department of Pharmacology, University of Virginia School of Medicine

Book Synopsis

Always a student favorite, Pharmacology for Nursing Care offers a clear approach explaining drug prototypes and how they work. It provides the background needed to understand related drugs currently on the market, as well as drugs yet to be released. In simplifying a complex subject, this text focuses on the essentials of pharmacology. Large print is used to show "need-to-know" information, and small print is used for "nice to know" material. At the end of each chapter, a summary of major nursing implications helps in applying the material to real-world situations. This edition includes a new companion CD-ROM featuring NCLEX(r) examination-style review questions, a variety of electronic calculators, and animations depicting drug mechanisms and effects.

  • Uses a prototype drug approach that places a strong emphasis on understanding over memorization - equipping students with the knowledge to learn not only about related drugs currently on the market, but also about those drugs that will be released once the student begins practice.
  • Summaries of Major Nursing Implications at the end of each chapter provide an in-depth look at assessment, implementation, and ongoing evaluations.
  • Utilizes large print for essential information and small print for "nice-to-know" information to help both faculty and students focus their limited classroom and study time on understanding the essentials.
  • Concise drug summary tables present detailed information on individual drugs, including class, generic and trade names, dosages, routes, and indications.
  • Key Points at the end of each chapter summarize content in a bulleted format to help students reviewimportant concepts.
  • Prototype drug discussions employ a clear and consistent format with separate headings for Mechanism of Action; Pharmacologic Effects; Pharmacokinetics; Therapeutic Uses; Adverse Effects; Drug Interactions; and Preparations, Dosage, and Administration.
  • An attractive full-color design adds visual interest, highlights key information, and facilitates student learning.


  • Drugs for Multiple Sclerosis and Drugs for Hemophilia chapters.
  • Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia chapter covers newsworthy drugs such as Viagra and Levitra.
  • Special Interest Topics boxes on current issues in pharmacology, such as Medication-Overuse Headache: Too Much of a Good Thing and Face Time with Botox.
  • Adult Immunization appendix summarizes the latest information on immunizations.
  • Numerous new illustrations show drug mechanisms and effects, and depict topics such as histologic changes in Alzheimer's disease and the movement of drugs following GI absorption.

Barbara Van de Castle

This is a very detailed pharmacology textbook. It covers many areas in great detail with appropriately applied physiology. The nursing components are integrated throughout the text as well as summarized into nursing implications at the end of most chapters. Each chapter has a list of key points for review. The purpose is to establish a knowledge base in the basic science of drugs and to demonstrate application in the clinical area. The purpose is met, but more case studies for easier clinical application could have been incorporated. This book also strives to focus on the essentials needed in nursing care and downplays secondary details by utilizing different sizes of print. This makes it easier to scan a page for important information. The target audience is nursing students in a pharmacology course. The level of physiology and detail may or may not be appropriate for integrated curricula. It is an excellent clinical review and resource for practitioners and educators. The references were few and located in the text instead of at the end of each chapter, which makes them difficult to locate. The content appears complete; new sections include Pediatric Immunization, Drug Therapy Across the Life Span, and an appendix for Drug-Related Information on the Internet. This list of Internet sites is appropriate and a great resource for the learner. The disk provided has a drug database of 200 drugs and NCLEX review questions. The review is easy to use and provides feedback on correct and incorrect answers. The database is very small and requires the students to actually cut and paste a card together. This textbook is an excellent resource and is suitable for a pharmacologycourse.

Table of Contents

1Orientation of pharmacology1
2Application of pharmacology in nursing practice5
3Drug regulation, development, names, and information15
4Pharmacokinetics25
5Pharmacodynamics46
6Drug interactions58
7Adverse drug reactions and medication errors65
8Individual variation in drug responses77
9Drug therapy during pregnancy and breast-feeding85
10Drug therapy in pediatric patients92
11Drug therapy in geriatric patients96
12Basic principles of neuropharmacology99
13Physiology of the peripheral nervous system105
14Muscarinic agonists and antagonists121
15Cholinesterase inhibitors and their use in myasthenia gravis132
16Drugs that block nicotinic cholinergic transmission : neuromuscular blocking agents and ganglionic blocking agents140
17Adrenergic agonists150
18Adrenergic antagonists163
19Indirect-acting antiadrenergic agents175
20Introduction to central nervous system pharmacology181
21Drugs for Parkinson's disease184
22Alzheimer's disease198
23Drugs for multiple sclerosis205
24Drugs for epilepsy215
25Drugs for muscle spasm and spasticity237
26Local anesthetics242
27General anesthetics249
28Opioid (narcotic) analgesics, opioid antagonists, and nonopioid centrally acting analgesics258
29Pain management in patients with cancer281
30Drugs for headache300
31Antipsychotic agents and their use in schizophrenia311
32Antidepressants330
33Drugs for bipolar disorder353
34Sedative-hypnotic drugs363
35Management of anxiety disorders378
36Central nervous systems stimulants and attention-deficit/hyperactivity disorder387
37Drug abuse I : basic considerations398
38Drug abuse II : alcohol405
39Drug abuse III : major drugs and abuse (other than alcohol)415
40Diuretics436
41Agents affecting the volume and ion content of body fluids449
42Review of hemodynamics454
43Drugs acting on the renin-angiotensin-aldosterone system461
44Calcium channel blockers473
45Vasodilators481
46Drugs for hypertension487
47Drugs for heart failure509
48Antidysrhythmic drugs526
49Prophylaxis of coronary heart disease : drugs that lower LDL cholesterol levels546
50Drugs for angina pectoris571
51Anticoagulant, antiplatelet, and thrombolytic drugs585
52Management of ST-elevation myocardial infarction609
53Drugs for hemophilia615
54Drugs for deficiency anemias623
55Hematopoietic growth factors637
56Drugs for diabetes mellitus646
57Drugs for thyroid disorders674
58Drugs related to hypothalamic and pituitary function686
59Drugs for disorders of the adrenal cortex695
60Estrogens and progestins : basic pharmacology and noncontraceptive applications703
61Birth control720
62Drug therapy of infertility737
63Drugs that affect uterine function745
64Androgens753
65Drugs for erectile dysfunction and benign prostatic hyperplasia761
66Review of the immune system768
67Childhood immunization779
68Immunosuppressants795
69Antihistamines802
70Cyclooxygenase inhibitors : nonsteroidal anti-inflammatory drugs and acetaminophen809
71Glucocorticoids in nonendocrine diseases827
72Drug therapy of rheumatoid arthritis and gout837
73Drugs affecting calcium levels and bone mineralization847
74Drugs for asthma866
75Drugs for allergic rhinitis, cough, and colds883
76Drugs for peptic ulcer disease891
77Laxatives904
78Other gastrointestinal drugs911
79Vitamins925
80Enteral and parenteral nutrition936
81Drugs for obesity940
82Basic principles of antimicrobial therapy948
83Drugs that weaken the bacterial cell wall I : penicillins962
84Drugs that weaken the bacteria cell wall II : cephalosporins, carbapenems, vancomycin, aztreonam, teicoplanin, and fosfomycin972
85Bacteriostatic inhibitors of protein synthesis : tetracyclines, macrolides, and others981
86Aminoglycosides : bactericidal inhibitors of protein synthesis994
87Sulfonamides and trimethoprim1002
88Drug therapy of urinary tract infections1009
89Antimycobacterial agents : drugs for tuberculosis, leprosy, and Mycobacterium avium complex infection1014
90Miscellaneous antibacterial drugs : fluoroquinolones, metronidazole, daptomycin, rifampin, bacitracin, and polymyxins1029
91Antifungal agents1035
92Antiviral agents I : drugs for non-HIV viral infections1048
93Antiviral agents II : drugs for HIV infection and related opportunistic infections1064
94Drug therapy of sexually transmitted diseases1107
95Antiseptics and disinfectants1115
96Anthelmintics1121
97Antiprotozoal drugs I : antimalarial agents1126
98Antiprotozoal drugs II : miscellaneous agents1133
99Extoparasiticides1139
100Basic principles of cancer chemotherapy1142
101Anticancer drugs I : cytotoxic agents1157
102Anticancer drugs II : hormonal agents, biologic response modifiers, and targeted drugs1172
103Drugs for the eye1191
104Drugs for the skin1201
105Drugs for the ear1217
106Miscellaneous noteworthy drugs1224
107Herbal supplements1234
108Management of poisoning1245
109Potential weapons of biologic, radiologic, and chemical terrorism1251

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