Neoplasms: Principles of Development and Diversity » (1E)

This Unique Text Is Devoted To The Full Range Of Neoplastic Properties Exhibited By The Comprehensive Collection Of Human Neoplasms. Like No Other Book Of It's Kind, It Approaches Cancer Biology By Surveying The Diversity Of Neoplasms And By Building A Classification Of Neoplasms Based On An Understanding Of The Cellular Options For Tumor Development. By Grouping Neoplasms Into A Comprehensive Classification, We Can Develop Class-Specific Methods To Prevent, Detect, And Treat Cancers. The Book Is Divided Into Three Broad Units: Speciation, Classification And Eradication. In The Process Of Developing A Classification For Neoplasms, Dozens Of The Fundamental Questions In Neoplastic Development Are Asked And Answered. Neoplasms Provides Readers With A Fascinating And Enjoyable Way To Learn The Otherwise Arcane And Dense Subject Of Human Tumor Diversity.

Introduction What Will You Learn by Reading This Book?

Pt. I Speciation 1

1 What Properties Are Shared by All Cancers? 3

2 Carcinogenesis 21

3 The Mysteries of Tumor Diversity and of Type-Specific Tumor Uniformity 42

4 The Range of Neoplastic Phenotypes 51

5 What Can We Learn About Human Neoplasms by Studying Animals, Plants, Fish, and Insects? 67

Pt. II Classification 85

6 What Does Classification of All Animals Tell Us About the Classification of All Neoplasms? 87

7 Classification of Neoplasms 93

8 Classification by Morphology (What the Tumor Looks Like) 100

9 Classification by Cause 128

10 Classification by Topography (Where the Tumor is Located) 144

11 Classification by the Age at which the Cancer Occurs 148

12 Classification by Function and Common Pathways 160

13 Molecular Classification of Neoplasms 168

14 Classification by Developmental Lineage Is Best 180

15 The Six Major Classes of Neoplasms 187

16 Ectodermal and Endodermal Neoplasms 198

17 Mesodermal Neoplasms 211

18 Tumors of Neuroectoderm (Brain and Central Nervous System) 220

19 Neural Crest Tumors 226

20 Tumors of Class Germ Cell and Class Trophectoderm 237

21 Specialized Cancer Nomenclatures and the Developmental Lineage Classification and Taxonomy of Neoplasms 251

22 Cancer Ontologies 263

Pt. III Cancer Research and the End of Neoplasms 273

23 Class-Dependent Cancer Prevention, Diagnosis, and Treatment 275

24 Finding Neoplasms: Suggestions for Cancer Researchers 292

25 Principles 302

Glossary 307

References 369

Index 395

Figure Credits 425

Author Biography 429