Molecular Cell Biology » (6th Edition)

Harvey Lodish is Professor of Biology and Professor of Bioengineering at the Massachusetts Institute of Technology and a member of the Whitehead Institute for Biomedical Research. Dr. Lodish is also a member of the National Academy of Sciences and the American Academy of Arts and Sciences and was President (2004) of the American Society for Cell Biology. He is well known for his work on cell membrane physiology, particularly the biosynthesis of many cell-surface proteins, and on the cloning and functional analysis of several cell-surface receptor proteins, such as the erythropoietin and TGF-ß receptors. His lab also studies hematopoietic stem cells and has identified novel proteins that support their proliferation. Dr. Lodish teaches undergraduate and graduate courses in cell biology and biotechnology.

Arnold Berk is Professor of Microbiology, Immunology and Molecular Genetics and a member of the Molecular Biology Institute at the University of California, Los Angeles. Dr. Berk is also a fellow of the American Academy of Arts and Sciences. He is one of the original discoverers of RNA splicing and of mechanisms for gene control in viruses. His laboratory studies the molecular interactions that regulate transcription nitiation in mammalian cells, focusing particular attention on transcription factors encoded by oncogenes and tumor suppressors. He teaches introductory courses in molecular biology and virology and an advanced course in cell biology of the nucleus.

Chris A. Kaiser is Professor and Head of the Department of Biology at the Massachusetts Institute of Technology. His laboratory uses genetic and cell biological methods to understand the basic processes of how newly synthesized membrane and secretory proteins are folded and stored in the compartments of the secretory pathway. Dr. Kaiser is recognized as a top undergraduate educator at MIT, where he has taught genetics to undergraduates for many years.

Monty Krieger is the Whitehead Professor in the Department of Biology at the Massachusetts Institute of Technology. For his innovative teaching of undergraduate biology and human physiology as well as graduate cell biology courses, he has received numerous awards. His laboratory has made contributions to our understanding of membrane trafficking through the Golgi apparatus and has cloned and characterized receptor proteins important for the movement of cholesterol into and out of cells, including the HDL receptor.

Matthew P. Scott is Professor of Developmental Biology, Genetics and Bioengineering at Stanford University School of Medicine and Investigator at the Howard Hughes Medical Institute. He is a member of the National Academy of Sciences and the American Academy of Arts and Sciences and a past president of the Society for Developmental Biology. He is known for his work in developmental biology and genetics, particularly in areas of cell-cell signaling and homeobox genes and for discovering the roles of developmental regulators in cancer. Dr. Scott teaches cell and developmental biology to undergraduate students, development and disease mechanisms to medical students and developmental biology to graduate students at Stanford University.

Anthony Bretscher is Professor of Cell Biology at Cornell University. His laboratory is well known for identifying and characterizing new components of the actin cytoskeleton, and elucidating their biological functions in relation to cell polarity and membrane traffic. For this work, his laboratory exploits biochemical, genetic and cell biological approaches in two model systems, vertebrate epithelial cells and the budding yeast. Dr. Bretscher teaches cell biology to graduate students at Cornell University.

Hidde Ploegh is Professor of Biology at the Massachusetts Institute of Technology and a member of the Whitehead Institute for Biomedical Research. One of the world’s leading researchers in immune system behavior, Dr. Ploegh studies the various tactics that viruses employ to evade our immune responses, and the ways in which our immune system distinguishes friend from foe. Dr. Ploegh teaches immunology to undergraduate students at Harvard University and MIT.

This is the new edition of a college level textbook on molecular cell biology. The emphasis is on experimental basis of current understandings. New experimental methodologies and concepts are introduced in this edition. Thirteen chapters cover such topics as biomembranes and cell architecture, cell integration in tissues, cell transport mechanisms, cellular energetics, molecular genetic techniques, transcriptional control of gene expression, and signaling at the cell surface. Annotation ©2003 Book News, Inc., Portland, OR

Alvin Telser

This is a fourth edition textbook on molecular cell biology. The third edition was published in 1995. The purpose is to convey the most current information and understanding of molecular and cellular biology to students of these topics. These are very worthwhile objectives and are fully attained. The book is written for advanced undergraduates -- biology, molecular biology, cell biology, and biochemistry majors as well as premedical students. This is an appropriate audience and the book is targeted to them very well. The authors are highly regarded experts in the material presented in this textbook. The full range of modern molecular and cellular biology is covered in over 1000 pages consisting of 24 chapters. The table of contents and index are extremely thorough. Each book comes with an excellent student CD-ROM containing eight useful features; e.g., animations, videos, practice questions, etc. There are other CD-ROMs available for instructors. The book is copiously illustrated with many excellent color diagrams, charts, photos, etc. There are no significant shortcomings. This is an outstanding textbook; the new edition is quite welcome in light of the many advances and new information in this field. It is very well written and organized. The main competition is Albert's Molecular Biology of the Cell, 3rd Edition (Garland Publishing, 1994), also an excellent textbook. This makes the choice of the professor rather difficult, but both books are models of excellence. Anyone using this book as it is intended will come away with a solid understanding of modern molecular and cellular biology.