You are not signed in. Sign in.

List Books: Buy books on ListBooks.org

Modern HPLC for Practicing Scientists » (1st Edition)

Book cover image of Modern HPLC for Practicing Scientists by Michael W. Dong

Authors: Michael W. Dong
ISBN-13: 9780471727897, ISBN-10: 047172789X
Format: Paperback
Publisher: Wiley, John & Sons, Incorporated
Date Published: June 2006
Edition: 1st Edition

Find Best Prices for This Book »

Author Biography: Michael W. Dong

MICHAEL W. DONG, PhD, is a Research Director at Synomics Pharma in Wareham, Massachusetts,responsible for chromatography method development and research studies. He has been a research fellow/group leader at Purdue Pharma, a senior staff scientist at PerkinElmer, and a section head at Hoechst Celanese. He holds a BSc in chemistry from Brooklyn College and a PhD in analytical chemistry from the City University of New York Graduate Center. Dr. Dong pioneered Fast LC and has over eighty publications in chromatography and analytical chemistry. He is the coeditor of another book on pharmaceutical analysis by HPLC, published in 2005.

Book Synopsis

A comprehesive yet concise guide to Modern HPLC

Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers.

Topics covered include:

  • HPLC operation
  • Method development
  • Maintenance and troubleshooting
  • Modern trends in HPLC such as quick-turnaround and "greener" methods
  • Regulatory aspects

While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources.

With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.

Table of Contents

1Introduction1
2Basic terms and concepts15
3HPLC columns and trends47
4HPLC instrumentation and trends77
5HPLC operation guide111
6Pharmaceutical analysis135
7Food, environmental, chemical, and life sciences applications157
8HPLC method development193
9Regulatory aspects of HPLC analysis : HPLC system and method validation221
10HPLC maintenance and troubleshooting guide243
11Modern trends in HPLC265

Subjects