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Lords of the Fly: Drosophila Genetics and the Experimental Life » (1st Edition)

Book cover image of Lords of the Fly: Drosophila Genetics and the Experimental Life by Robert E. Kohler

Authors: Robert E. Kohler
ISBN-13: 9780226450636, ISBN-10: 0226450635
Format: Paperback
Publisher: University of Chicago Press
Date Published: January 1994
Edition: 1st Edition

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Author Biography: Robert E. Kohler

Book Synopsis

The common fruit fly, Drosophila, has long been one of the most productive of all laboratory animals. From 1910 to 1940, the center of Drosophila culture in America was the school of Thomas Hunt Morgan and his students Alfred Sturtevant and Calvin Bridges. They first created "standard" flies through inbreeding and by organizing a network for exchanging stocks of flies that spread their practices around the world.

In Lords of the Fly, Robert E. Kohler argues that fly laboratories are a special kind of ecological niche in which the wild fruit fly is transformed into an artificial animal with a distinctive natural history. He shows that the fly was essentially a laboratory tool whose startling productivity opened many new lines of genetic research. Kohler also explores the moral economy of the "Drosophilists": the rules for regulating access to research tools, allocating credit for achievements, and transferring authority from one generation of scientists to the next.

By closely examining the Drosophilists' culture and customs, Kohler reveals essential features of how experimental scientists do their work.

Table of Contents

List of Illustrations
Preface
1The Nature of Experimental Life1
2Crossing the Threshold19
3Constructing Drosophila53
4The Fly People91
5The Drosophila Exchange Network133
6Improvisations173
7Reconstructing Drosophila: Developmental Genetics208
8From Laboratory to Field: Evolutionary Genetics250
Appendix295
Abbreviations301
Bibliography303
Index315

Subjects