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Fundamentals of Biochemistry: Life at the Molecular Level » (3rd Edition)

Book cover image of Fundamentals of Biochemistry: Life at the Molecular Level by Donald Voet

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt
ISBN-13: 9780470279892, ISBN-10: 0470279893
Format: Other Format
Publisher: Wiley, John & Sons, Incorporated
Date Published: January 2008
Edition: 3rd Edition

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Author Biography: Donald Voet

Donald Voet received a B.S. in Chemistry from the California Institute of Technology, a Ph.D. in Chemistry from Harvard University with William Lipscomb, and did postdoctoral research in the Biology Department at MIT with Alexander Rich. Upon completion of his postdoctoral research, Don took up a faculty position in the Chemistry Department at the University of Pennsylvania where, for the past 38 years, he has taught a variety of Biochemistry courses as well as general Chemistry. His major area of research is the X-ray crystallography of molecules of biological interest. He has been a visiting scholar at Oxford University, The University of California at San Diego, and the Weizmann Institute of Science in Israel. Together with Judith G. Voet, he is Co-Editor-in-Chief of the journal Biochemistry and Molecular Biology Education. He is a member of the Education Committee of the International Union of Biochemistry and Molecular Biology. His hobbies include backpacking, scuba diving, skiing, travel, photography, and writing Biochemistry textbooks.

Judith ("Judy") Voet received her B.S. in Chemistry from Antioch College and her Ph.D. in Biochemistry from Brandeis University with Robert H. Abeles. She has done postdoctoral research at the University of Pennsylvania, Haverford College, and the Fox Chase Cancer Center. Her main area of research involves enzyme reaction mechanisms and inhibition. She taught Biochemistry at the University of Delaware before moving to Swarthmore College. She taught there for 26 years, reaching the position of James H. Hammons Professor of Chemistry and Biochemistry before going on "permanent sabbatical leave." She has been a visiting scholar at Oxford University, University of California, San Diego, University of Pennsylvania, and the Weizmann Institute of Science, Israel. She is Co-Editor-in-Chief of the journal Biochemistry and Molecular Biology Education. She has been a member of the Education and Professional Development Committee of the American Society for Biochemistry and Molecular Biology as well as the Education Committee of the International Union of Biochemistry and Molecular Biology. Her hobbies include hiking, backpacking, scuba diving, and tap dancing.

Charlotte Pratt received her B.S. in Biology from the University of Notre Dame and her Ph.D. in Biochemistry from Duke University under the direction of Salvatore Pizzo. Although she originally intended to be a marine biologist, she discovered that Biochemistry offered the most compelling answers to many questions about biological structure-function relationships and the molecular basis for human health and disease. She conducted postdoctoral researching the Center for Thrombosis and Hemostasis at the University of North Carolina at Chapel Hill. She has taught at the University of Washington and currently teaches at Seattle Pacific University. In addition to working as an editor of several Biochemistry textbooks, she has co-authored Essential Biochemistry and previous editions of Fundamentals of Biochemistry.

Book Synopsis

Understand what you don't know!

WileyPLUS for the new third edition of FUNDAMENTALS OF BIOCHEMISTRY now offers over 750 conceptually-based online questions, organized by chapter and topic. These original questions were created by biochemistry Professors at University of Alberta, and have bee3n tested and used since 2000.

Now in WileyPLUS, these questions offer practice with instant intelligent feedback that explains why an answer choice is right or wrong.

WileyPLUS also contains:

  • Complete online version of FUNDAMENTALS OF BIOCHEMISTRY, Third Edition

  • Guided Explorations and Interactive Exercises that enhance comprehension through animated graphics and narration

  • Animated Figures from the text

  • Bioinformatics Exercises

  • Case Studies

  • 3D molecular models

Booknews

Donald Voet (U. of Pennsylvania) and Judith G. Voet (Swarthmore), two of this text's three authors (the third is Charlotte W. Pratt) already have under their belts a larger text, . The present text retains the philosophy of the earlier book, but it is less detailed and constitutes a re-vamped treatment of the subject both in organization and style. The material is organized to correspond with how the authors teach the course, but detailed division into sections and subsections allows instructors with other ideas to organize courses to their own tastes without apprehension that they've missed critical information. The included CD-ROM contains a variety of interactive three-dimensional molecular graphics displays and animations. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Table of Contents

Ch. 1Introduction to the chemistry of life2
Ch. 2Water22
Ch. 3Nucleotides, nucleic acids, and genetic information40
Ch. 4Amino acids76
Ch. 5Proteins : primary structure94
Ch. 6Proteins : three-dimensional structure129
Ch. 7Protein function : myoglobin and hemoglobin181
Ch. 8Carbohydrates206
Ch. 9Lipids and biological membranes233
Ch. 10Membrane transport284
Ch. 11Enzymatic catalysis312
Ch. 12Enzyme kinetics, inhibition, and regulation357
Ch. 13Introduction to metabolism395
Ch. 14Glucose catabolism427
Ch. 15Glycogen metabolism and gluconeogenesis472
Ch. 16Citric acid cycle514
Ch. 17Electron transport and oxidative phosphorylation545
Ch. 18Photosynthesis590
Ch. 19Lipid metabolism627
Ch. 20Amino acid metabolism682
Ch. 21Mammalian fuel metabolism : integration and regulation743
Ch. 22Nucleotide metabolism787
Ch. 23Nucleic acid structure817
Ch. 24DNA replication, repair, and recombination867
Ch. 25Transcription and RNA processing919
Ch. 26Translation960
Ch. 27Regulation of gene expression1010
Ch. 28Protein function part II : cytoskeletal and motor proteins and antibodies1072
AppBioinformatics exercises1115
AppAnswers to bioinformatics exercises1124

Subjects