Coccidioidomycosis: Sixth International Symposium »

David Stevens is the winner of eleven Chelsea Flower Show gold medals. He has hosted two popular garden design series on television and is the author of many successful gardening books. He lives in England.

The proceedings of the sixth conference on Coccidioidomycosis presents state of the art overviews of our current understandings of this fungal disease and the causative organism. This is an emerging infectious disease, with cases increasing especially in the Southwest US. The volume should be of interest to medical mycologists, infectious disease especialists, fungal biologists, and immunologists.

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Preface   Karl V. Clemons   Rafael Laniado-Laborin   David A. Stevens     xi
Grand Rounds
Coccidioidomycosis: Changing Perceptions and Creating Opportunities for Its Control   John N. Galgiani     1
Epidemiology and Public Health
Expanding Understanding of Epidemiology of Coccidioidomycosis in the Western Hemisphere   Rafael Laniado-Laborin     19
Ecological Niche Modeling of Coccidioides spp. in Western North American Deserts   Raul C. Baptista-Rosas   Alejandro Hinojosa   Meritxell Riquelme     35
Coccidioides Niches and Habitat Parameters in the Southwestern United States: A Matter of Scale   Frederick S. Fisher   Mark W. Bultman   Suzanne M. Johnson   Demosthenes Pappagianis   Erik Zaborsky     47
Fluctuations in Climate and Incidence of Coccidioidomycosis in Kern County, California: A Review   Jorge Talamantes   Sam Behseta   Charles S. Zender     73
Assessment of Climate-Coccidioidomycosis Model: Model Sensitivity for Assessing Climatologic Effects on the Risk of Acquiring Coccidioidomycosis   Andrew C. Comrie   Mary F. Glueck     83
Public Health Surveillance for Coccidioidomycosis in Arizona   Rebecca H. Sunenshine   Shoana Anderson   Laura Erhart   AnneVossbrink   Peter C. Kelly   David Engelthaler   Kenneth Komatsu     96
Coccidioidomycosis in California State Correctional Institutions   Demosthenes Pappagianis$dThe Coccidioidomycosis Serology Laboratory     103
Coccidioidomycosis in the U.S. Military: A Review   Nancy F. Crum-Cianflone     112
Coccidioidomycosis Infection in a Predominantly Hispanic Population   Miguel Angel Pena-Ruiz   Armando D. Meza   Zuber D. Mulla     122
Compensability of, and Legal Issues Related to, Coccidioidomycosis   Luann Haley     129
Basic Research Studies
The Application of Proteomic Techniques to Fungal Protein Identification and Quantification   James G. Rohrbough   John N. Galgiani   Vicki H. Wysocki     133
The Population Biology of Coccidioides: Epidemiologic Implications for Disease Outbreaks   B. M. Barker   K. A. Jewell   S. Kroken   M. J. Orbach     147
Molecular Cloning and Expression of a cDNA Encoding a Coccidioides posadasii 1,2-[alpha]-Mannosidase Identified in the Coccidioidal T27K Vaccine by Immunoproteomic Methods   Jennine M. Lunetta   Keira A. Simmons   Suzanne M. Johnson   Demosthenes Pappagianis     164
Molecular Cloning and Expression of a cDNA Encoding a Coccidioides posadasii Cu,Zn Superoxide Dismutase Identified by Proteomic Analysis of the Coccidioidal T27K Vaccine   Jennine M. Lunetta   Keira A. Simmons   Suzanne M. Johnson   Demosthenes Pappagianis     181
Nuclear Labeling of Coccidioides posadasii with Green Fluorescent Protein   Lei Li   Monika Schmelz   Ellen M. Kellner   John N. Galgiani   Marc J. Orbach     198
Experimental Animal Models of Coccidioidomycosis   Karl V. Clemons   Javier Capilla   David A. Stevens     208
Virulence Mechanisms of Coccidioides   Chiung-Yu Hung   Jianmin Xue   Garry T. Cole     225
The Role of IL-10 in Genetic Susceptibility to Coccidioidomycosis on Mice   Joshua Fierer     236
The Complex Immunology of Human Coccidioidomycosis   Neil M. Ampel     245
Vaccine Research
The Public Health Need and Present Status of a Vaccine for the Prevention of Coccidioidomycosis   Richard Hector   George W. Rutherford     259
Dendritic Cell-Based Vaccine against Coccidioides Infection   Shanjana Awasthi     269
Characteristics of the Protective Subcellular Coccidioidal T27K Vaccine   Suzanne M. Johnson   Kathleen M. Kerekes   Jennine M. Lunetta   Demosthenes Pappagianis     275
Safety, Antigenicity, and Efficacy of a Recombinant Coccidioidomycosis Vaccine in Cynomolgus Macaques (Macaca fascicularis)   Suzanne M. Johnson   Nicholas W. Lerche   Demosthenes Pappagianis   Joann L. Yee   John N. Galgiani   Richard F. Hector     290
Laboratory Diagnosis
Laboratory Aspects in the Diagnosis of Coccidioidomycosis   Michael A. Saubolle     301
Diagnosis of Coccidioidomycosis by Culture: Safety Considerations, Traditional Methods, and Susceptibility Testing   Deanna A. Sutton     315
Molecular Identification of Coccidioides Isolates from Mexican Patients   Laura Rocio Castanon-Olivares   Diego Guerena-Elizalde   Marisela Rocio Gonzalez-Martinez   Alexei Fedorovich   Licea-Navarro   Gloria Maria Gonzalez-Gonzalez   Arturo Aroch-Calderon|p326
Clinical Disease
Coccidioidomycosis in Persons Infected with HIV-1   Neil M. Ampel     336
Coccidioidomycosis in Rheumatology Patients: Incidence and Potential Risk Factors   Lester E. Mertz   Janis E. Blair     343
Coccidioidomycosis and Pregnancy: A Review   Irene M. Spinello   Royce H. Johnson   Shehla Baqi     358
Coccidioidomycosis in Patients Who Have Undergone Transplantation   Janis E. Blair     365
Coccidioidal Meningitis   Paul L. Williams     377
Deep Solitary Brain Mass in a Four-Month-Old Male with Disseminated Coccidioidomycosis: Case Report   Jennifer D. Nolt   Francesca R. Geertsma     385
Veterinary Infection
Comparative Aspects of Coccidioidomycosis in Animals and Humans   Lisa F. Shubitz     395
Diagnosis and Treatment of Ocular Coccidioidomycosis in a Female Captive Chimpanzee (Pan troglodytes): A Case Study   K. Hoffman   E. N. Videan   J. Fritz   J. Murphy     404
Therapy
State-of-the-Art Treatment of Coccidioidomycosis: Skin and Soft-Tissue Infections   Janis E. Blair     411
State-of-the-Art Treatment of Coccidioidomycosis Skeletal Infections   Janis E. Blair     422
Amphotericin B and Coccidioidomycosis   Royce H. Johnson   Hans E. Einstein     434
Azole Therapy of Clinical and Experimental Coccidioidomycosis   David A. Stevens   Karl V. Clemons     442
Poster Presentations     455
Index of Contributors     461