Biological Reactive Intermediates V, Vol. 387 » (New Edition)

An oxidant sensor at the plasma membrane/role of molecular biology in risk assessment/etc.

Booknews

Papers from the symposium detail advances in the chemistry and formation of reactive intermediates, cellular damage and control of gene expression by biological reactive intermediates, organ specific effects, organ-organ interactions, modeling of bioactivation reactions, and the relationship between mechanistic studies and risk assessment. The research stems from the finding that xenobiotic chemicals enter the body from the environment, are metabolized to highly reactive species, and then covalently react with cellular macromolecules to induce toxic and carcinogenic effects in humans. Annotation c. Book News, Inc., Portland, OR (booknews.com)