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Advanced Practical Organic Chemistry » (2nd Edition)

Book cover image of Advanced Practical Organic Chemistry by John Leonard

Authors: John Leonard, Garry Procter, Barry Lygo, Barry Lygo
ISBN-13: 9780748740710, ISBN-10: 0748740716
Format: Paperback
Publisher: Taylor & Francis, Inc.
Date Published: June 1994
Edition: 2nd Edition

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Author Biography: John Leonard

Book Synopsis

The first edition of this book achieved considerable success due to its ease of use and practical approach, and to the clear writing style of the authors. The preparation of organic compounds is still central to many disciplines, from the most applied to the highly academic and, more tan ever is not limited to chemists. With an emphasis on the most up-to-date techniques commonly used in organic syntheses, this book draws on the extensive experience of the authors and their association with some of the world's mleading laboratories of synthetic organic chemistry. In this new edition, all the figures have been re-drawn to bring them up to the highest possible standard, and the text has been revised to bring it up to date.

Written primarily for postgraduate, advanced undergraduate and industrial organic chemists, particularly those involved in pharmaceutical, agrochemical and other areas of fine chemical research, the book is also a source of reference for biochemists, biologists, genetic engineers, material scientists and polymer researchers.

Booknews

A guide to the preparation of organic compounds and types of reactions used in modern organic synthesis, emphasizing recent techniques. Covers lab basics such as safety, record keeping, and equipment, presents techniques for working with solvents, reagents, gases, and vacuum pumps, and details carrying out reactions, purification, and characterization. Includes a review of the chemical literature, and appendices listing properties of solvents, gases, reducing reagents, and oxidizing reagents. For postgraduates and advanced undergraduates. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Table of Contents

1General Introduction1
2Safety3
3Keeping records of laboratory work8
4Equipping the laboratory and the bench36
5Purification and drying of solvents54
6Reagents: Preparation, purification and handling69
7Gases107
8Vacuum pumps122
9Carrying out the reaction128
10Working up the reaction177
11Purification184
12Small scale reactions227
13Large scale reactions236
14Special procedures240
15Characterization250
16'Trouble shooting'; what to do when things don't work258
17The chemical literature262
Appendix 1. Properties of common solvents277
Appendix 2. Properties of common gases278
Appendix 3. Approximate pKa values for some common deprotonations compared to some common bases279
Appendix 4. Lewis acids280
Appendix 5. Common reducing reagents281
Appendix 6. Common oxidizing reagents285
Index289

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