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Thomas F. Lee
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Conquering Rheumatoid Arthritis: The Latest Breakthroughs and Treatments Paperback – June 1, 2001

by Thomas F. Lee (Author)
4.6 4.6 out of 5 stars 9 ratings
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As a biologist with more than thirty years of experience teaching a wide range of complex biomedical subjects and a person who suffers from rheumatoid arthritis (RA) himself, Dr. Thomas F. Lee is ideally suited to write a book that addresses the vital questions about the nature of the disease and the rationale behind its treatment. This is the only book that explains in layperson's terms the newest available therapies and the latest advances in our understanding of this often debilitating disease. These new insights have led to many molecular-based approaches already in clinical trial, and many more are waiting in the wings. All of these exciting developments are the result of the ongoing biotechnological revolution and a new understanding of the immune system aided by genetic research.Over two million people in this country suffer from rheumatoid arthritis (RA), a debilitating autoimmune disease that ravages the delicate lining of the joints. As in other autoimmune diseases, instead of defending against foreign invaders, the immune system inexplicably attacks healthy tissue. RA causes systemic effects as well; not only are joints painful, through the destruction of bone and cartilage, but there is often accompanying fatigue, decreased appetite, depression, and muscle pain.Dr. Lee not only supplies you with the latest facts on the discoveries about the disease, but he also provides numerous Web sites so that readers can follow this important story as it unfolds.
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Previous page
  1. Print length
    256 pages
  2. Language
    English
  3. Publisher
    Prometheus
  4. Publication date
    June 1, 2001
  5. Dimensions
    6 x 0.5 x 9 inches
  6. ISBN-10
    1573928860
  7. ISBN-13
    978-1573928861
  8. See all details
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Editorial Reviews

From Library Journal

The cause and treatment of many diseases is being advanced on a molecular level, an area of science and medicine not easily understood by the average person. Lee (microbiology and biotechnology, St. Anselm Coll.; The Human Genome Project) here attempts to make sense of recent research in rheumatoid arthritis (RA), focusing on the evolution of molecular and gene-based therapies for this autoimmune disease, which affects two million adults and children in the United States. Lee offers detailed scientific explanations of RA, an overview of the immune system and its role in the disease, and a description of the inflammatory sequence that launches RA. He then discusses the multibillion-dollar research efforts by universities, biotechnology centers, and the pharmaceutical industry to develop gene-based therapies and follows up with a discussion of the nature of clinical trials and a survey of therapies currently in the pharmaceutical pipeline. Lee mentions the ethical implications of human genome research but admits that it is not the intent of his book to discuss this area of debate thoroughly. Recommended for consumer health collections. Lisa L. McCormick, Jewish Hosp. Health Sciences Lib., Cincinnati
Copyright 2001 Reed Business Information, Inc.

Review

"Lee looks at advances in research, notes Web sites that have further information about these studies... a hopeful perspective for people with the disease." -- Science News

"Should be required reading for every person with rheumatoid arthritis and their physicians!" -- Arthritis Insight website, August 12, 2001

"Writing from personal experience as a rheumatoid arthritis sufferer, biologist Lee offers insight into this painful, progressive disease..." -- Science News, June 9th, 2001

"a plethora of information on treatment regimens, clinical trials currently underway and resources leading to innovative, future treatments." -- Advance for Nurses, January 20, 2003

Product details

  • Publisher ‏ : ‎ Prometheus; First Edition (June 1, 2001)
  • Language ‏ : ‎ English
  • Paperback ‏ : ‎ 256 pages
  • ISBN-10 ‏ : ‎ 1573928860
  • ISBN-13 ‏ : ‎ 978-1573928861
  • Item Weight ‏ : ‎ 12.5 ounces
  • Dimensions ‏ : ‎ 6 x 0.5 x 9 inches
  • Customer Reviews:
    4.6 4.6 out of 5 stars 9 ratings

About the author

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Thomas F. Lee

Thomas F. Lee

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Thomas Lee is a retired biology professor. Among other pursuits, he spends time writing, reading, and advocating pacifism and nonviolence. He and his wife Eileen have six children and five grandchildren. He is continuing his writing in the form of novels. His first novel, "IN THE END", a murder mystery set on a Catholic college campus, is available on Amazon as a Kindle ebook or paperback. Recently, his memoirs of boyhood, "On Being a Kid in the 1940s" has appeared on Amazon. His latest book is a novel dealing with the crisis created by the absurd brandishing of nuclear weapons. It is "The Warning: A Novel for the Nuclear Age."

Customer reviews

4.6 out of 5 stars
4.6 out of 5
9 global ratings

Top reviews from the United States

Bayou Boogie Man
5.0 out of 5 stars Well satisfied
Reviewed in the United States on April 10, 2013
Verified Purchase
Slightly used book but I got it at a bargain price.Contains good information thats easy to understand.I'm glad I bought it !
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Patricia S. Rowell
4.0 out of 5 stars Good source of RA info
Reviewed in the United States on October 20, 2013
Verified Purchase
When you are battling RA, you need to be as well informed as possible. This book has some helpful info, especially for those newly diagnosed.
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C. Williams
5.0 out of 5 stars Finally, a comprehensive discussion of RA we can understand.
Reviewed in the United States on April 2, 2004
This discussion on RA is the most comprehensive available in layman's terms.This disease process is so complicated and the research on treatment so varied, trying to keep up on journal articles or short publications is almost impossible. This book puts more useable information between the two covers than you will find anywhere. Unlike medical journals, the disease process explanations are concise and understandable. Although the explanations are detailed and scientific and may take more than one reading to get your brain around the complex concepts, it nicely falls somewhere in between the very oversimplified information found in "arthritis" books available at bookstores and over-complicated and hard-to-read medical book information. Truly helpful is the detail about how clinical trials are conducted and the complicated sequence of events that occur in treatment research. It makes the waiting for decades for new treatments a little easier to understand. Also helpful are the briefs on current research (now a bit out of date-some of the "in trials" treatments in the book have been approved and are available) that is ongoing along with web sites so individuals can follow trials, results, research progress, etc. and even contains information on joining in some of the clinical trials. The description of the immune processes is very helpful. Not only does it help the reader understand the immune system as a whole, and the effect of this disease on the immune system, it also gives a good picture of how HIV and AIDS compares on the opposite end of the immunity spectrum (overactive vs. underactive immune system). Best of all, this book arms RA sufferers with good information to be able to take a more active role in their own treatment. Buy it for a friend who has RA or buy it for yourself. You will want to reread it several times.
19 people found this helpful
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Lurch 57
4.0 out of 5 stars Four Stars
Reviewed in the United States on July 20, 2014
wife likes it
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Maureen E. Levine, Ph.D.
5.0 out of 5 stars Best Gift for someone with rheumatoid arthritis!
Reviewed in the United States on January 22, 2003
If you have rheumatoid arthritis, or if a friend or loved one has been diagnosed with this disease I highly recommend this book as an invaluable source of information. Not only is it packed with facts on rheumatoid arthritis ranging from details of exactly what is happening in the joints and the immune system to useful Web sites to keep up on the latest details on new medications and treatment approaches, it is also clearly and beautifully written. It really is a handbook to help readers make informed decisions with their physcians. Included as well are fascinating insights into possible future treatments now in the research stage - from the use of stem cells to gene therapy.
This is the best gift you can give a friend who suffers from RA.
17 people found this helpful
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Amazon Customer
4.0 out of 5 stars Easy to read
Reviewed in the United States on January 4, 2009
Great book for someone newly diagnosed with RA. Especially for someone who likes, "how stuff works". Offers an extensive list of websites in the back for further fact gathering and keeping up to date. Also a good resource for navigating and understanding the disease process and progression & the medicines available. I wish there had been a nod to, Dr. John E Sarno's (professor, Rehabilitation Medicine at the New York University School of Medicine) work and experience with treating RA and other mindbody disorders. If you are reading this review and have an interest his most recent book (2007) "The Divided Mind" is well worth taking a look at. I think it is important to keep an open mind, keep digging and find what works for you.
4 people found this helpful
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