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Carl-Ivar Brändén
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Introduction to Protein Structure 2nd Edition

by Carl Branden (Author), John Tooze (Author)
4.4 4.4 out of 5 stars 61 ratings
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Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions.

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Previous page
  1. ISBN-10
    9780815323051
  2. ISBN-13
    978-0815323051
  3. Edition
    2nd
  4. Publisher
    Garland Science
  5. Publication date
    January 1, 1999
  6. Language
    English
  7. Dimensions
    8.5 x 0.5 x 11.25 inches
  8. Print length
    410 pages
  9. See all details
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Editorial Reviews

Review

"The strength of the book lies in its beautiful art work and its logical dissection of the baffling complexities of protein structures…admirably concise, lucid and accurate presentations of difficult concepts…invaluable for students…" Nature

"As an introduction to what proteins look like, how they fold up and how they interact with other molecules, large and small this book has no peer. It will be invaluable to students and research workers." Trends in Biotechnical Sciences

"As usual, the distillation is authoritative and breathtaking." Tom Alber, University of California, Berkeley

"It is superb. It gives a terrific overview, with great breadth and a proper and fair weight to the subject it treats." Ken Dill, University of California, San Francisco

About the Author


Carl Branden

was educated at Uppsala University (PhD) and the MRC Laboratory for Molecular Biology, Cambridge, where he was a postdoctoral fellow in the laboratory of J.C. Kendrew. He has pursued a career in basic research, science administration (as science advisor to the Swedish Government), and biotechnology. Formerly Research Director of the European Synchrotron Radiation Facility in Grenoble, France, he is now at the Microbiology and Tumor Biology Center at the Karolinska Institute in Stockholm. A protein crystallographer with a distinguished academic career in research and teaching, he has made major contributions to the understanding of many biological structures, and is an editor of Structure.

John Tooze

was educated at Cambridge University (MA), London University (PhD) and Harvard University (where he was a postdoctoral fellow in the laboratory of J.D. Watson). After several years in basic research, he moved principally into science administration and science publishing, notably as the executive secretary of the European Molecular Biology Organisation, Heidelberg, Germany. He is currently Director of Support Services at the Imperial Cancer Research Fund Laboratories, London, and editor of EMBO Journal. A molecular biologist, his previous books include Molecular Biology of Tumor Viruses, The DNA Story (with J.D. Watson) and the very successful first edition of Recombinant DNA: A Short Course (with J.D. Watson and D.T. Kurtz).

Product details

  • ASIN ‏ : ‎ 0815323050
  • Publisher ‏ : ‎ Garland Science; 2nd edition (January 1, 1999)
  • Language ‏ : ‎ English
  • Paperback ‏ : ‎ 410 pages
  • ISBN-10 ‏ : ‎ 9780815323051
  • ISBN-13 ‏ : ‎ 978-0815323051
  • Item Weight ‏ : ‎ 2.31 pounds
  • Dimensions ‏ : ‎ 8.5 x 0.5 x 11.25 inches
  • Customer Reviews:
    4.4 4.4 out of 5 stars 61 ratings

About the author

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Carl-Ivar Brändén

Carl-Ivar Brändén

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Customer reviews

4.4 out of 5 stars
4.4 out of 5
61 global ratings

Top reviews from the United States

ROB BROWN
5.0 out of 5 stars Basics of Protein Structure - Great for revision!
Reviewed in the United States on November 23, 2005
Verified Purchase
I used this book a lot for one of my undergraduate courses three years back. It's excellent at explaining the fundamentals of protein structure, it's written very clearly and the diagrams are easy to understand and appropriate. I found it particularly useful when studying immunology, the explanation of immunoglobulin structure, splicing, and mechanism of action was better than some of the other textbooks I used from the library. I finally bought a copy as reference and to aid revision of some basics while applying for research associate positions within the biochemistry field.
4 people found this helpful
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Scott MacHaffie
4.0 out of 5 stars Good but outdated
Reviewed in the United States on January 22, 2021
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This book is good, but it's also old, so it is missing the last 20-30 years worth of protein structures and information that has come out since then. It is a good introduction to protein structure, but you should consider getting a more recent book as well to see what modern research has discovered.
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James Niland
5.0 out of 5 stars Great Introduction to Protein Strucutre for Novice
Reviewed in the United States on December 12, 2010
Verified Purchase
I bought this book to improve my play on fold.it
I am interested in science but have no qualifications in it.

This book is VERY approachable even for an uneducated person like me.
Also it has improved my understanding of protein structures a lot and my score on fold.it :O)
One person found this helpful
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C. Figueroa Miranda
5.0 out of 5 stars Fast delivery, book in excellent conditions
Reviewed in the United States on April 14, 2010
Verified Purchase
The book is completely new as the description said. I received it in 2 days
One person found this helpful
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wiredweird
5.0 out of 5 stars One of the best science books ever
Reviewed in the United States on September 22, 2003
This book was a pleasant surprise in almost every respect. I found it a gentle, clear exposition of material that can be hugely complicated. The text works upwards from amino acids, the building blocks, through the interactions of shape and chemical affinity, to views of proteins in action. By the time they appear, muscle fibers and virus capsules follow naturally from the discussion. This gives simple, concise descriptions of how proteins' shape emerge from its sequence. It goes on to describe protein control of DNA, to explain virus and muscle structure, and to hint at modern drug design.
'Protein Structure' requires some background in organic chemistry and in the ideas of molecular genetics. For example, you should already be familiar with steric hindrance and with the idea of regulatory regions in DNA. Branden and Tooze reward the prepared reader with a well-considered series of discussions. These include enzyme action, photosynthesis, virus self-assembly, muscle fibers, DNA binding, and more. I had never seen an actual chain of chemical events that turn light into usable chemical energy. This book stepped through it (for a bacterium, at least) in just few paragraphs and drawings. But the whole book is like that - it sustains a remarkable density of information, always in a very readable style.
The text is laid out in a simple and appealing way, and is profusely illustrated. The illustration is one of this book's wonderful strengths. Almost all of the discussion is carried in diagrams as well as in words, and the authors freely use as many different diagrams as needed to make each idea understandable. The illustration style is simple and consistent; most drawings use one of three or four conventions for describing proteins. Almost all of the illustrations seem to be hand-drawn with colored pencil. Still, the corpus of illsutrations is among the most communicative I have seen in any book. Artists aspiring to illustrate science (or to communicate any idea) should read Tufte, then treat this book as a uniquely successful case study.
My only complaint about this book had to do with the quality of its printing. A few pages in my copy have bad register, colors are not consistent from page to page, and the one major photograph is weirdly over-sharpened. I must also admit that I do not need a deep knowledge of protein structure and function - I scanned the book quickly, and read only parts with care. The book repaid that effort richly, and I expect that it will reward more careful readers even more. I'm not a biochemist, but I strongly recommend 'Protein Structure' to anyone at all interested in the topic.
29 people found this helpful
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Kristen S
4.0 out of 5 stars A bit out of date, but a good introduction to biomolecular structure
Reviewed in the United States on December 5, 2018
Verified Purchase
As long as you keep in mind that this is an older book, it is a good overview of biomolecular structure. Some sections are written with more clarity than others and subjects are somewhat patchy, but overall it's a very nice textbook (especially as a supplement).
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Alex H.
5.0 out of 5 stars Well written, well organized
Reviewed in the United States on August 12, 2013
Quite a well written book that manages to do an excellent job introducing the complexities of protein structural and the nuances of protein structural analysis, despite being fundamentally limited by the fact that it must be presented in a 2D manner. Very well written, and it does a good job building off of secondary structures and motifs to highlight functional characteristics of many diverse protein domains. Well written, and an excellent introductory book to the subject.
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Flordelis
1.0 out of 5 stars One Star
Reviewed in the United States on January 3, 2018
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Not good.
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Top reviews from other countries

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K V Nageswar
5.0 out of 5 stars Classic
Reviewed in India on September 21, 2020
Verified Purchase
A good introductory book to learn about the structure and function of proteins. Contains wonderful illustrations of protein structures. Will serve as a good companion book to textbooks of molecular biology, biochemistry, and cell biology.
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Client d'Amazon
5.0 out of 5 stars Très bon service
Reviewed in France on October 5, 2019
Verified Purchase
C'est un livre fondamental de la discipline. Il a été livré très rapidement
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Alessandro Nutini
5.0 out of 5 stars Great book !
Reviewed in Italy on April 23, 2017
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A great book about protein structure, maybe a bit old, but very clear and explanatory. I highly recommend it to anyone who is approaching protein biochemistry and professionals too.
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Volmir Chiarello
5.0 out of 5 stars Five Stars
Reviewed in the United Kingdom on June 29, 2015
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good
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Aveith
5.0 out of 5 stars Solide Basis zum Aufbau und Funktion von Proteinen
Reviewed in Germany on March 13, 2015
Verified Purchase
Ein Klassiker. Habe das Ebook für eine Prüfung geordert und es hat sich ausgezahlt. Das Buch hat einen guten Aufbau und gibt einen Einblick in den Aufbau und die Funktion von Proteinen. Super für Einsteiger in die Materie.
2 people found this helpful
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